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1

Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five US Medical Centers

Dunnenberger, Henry M., Crews, Kristine R., Hoffman, James M., Caudle, Kelly E., Broeckel, Ulrich, Howard, Scott C., Hunkler, Robert J., Klein, Teri E., Evans, William E., Relling, Mary V.

Journal:

Annual Review of Pharmacology

Year:

2015

Language:

english

File:

PDF, 819 KB

english, 2015

2

Incorporating a Genetic Risk Score into Coronary Heart Disease Risk Estimates: Effect on LDL Cholesterol Levels (the MIGENES Clinical Trial)

Kullo, Iftikhar J., Jouni, Hayan, Austin, Erin E., Brown, Sherry-Ann, Kruisselbrink, Teresa M., Isseh, Iyad N., Haddad, Raad A., Marroush, Tariq S., Shameer, Khader, Olson, Janet E., Broeckel, Ulrich,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.09 MB

english, 2016

3

Induced regulatory T cell-derived interleukin 10 is required for the cure of experimental colitis

Schmitt, Erica, Haribhai, Dipica, Williams, Jason, Aggarwal, Praful, Broeckel, Ulrich, Salzman, Nita, Williams, Calvin

Journal:

Inflammatory Bowel Diseases

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

4

Ischemia reperfusion injury as a modifiable therapeutic target for cardioprotection or neuroprotection in patients undergoing cardiopulmonary resuscitation

Madathil, Ronson J., Hira, Ravi S., Stoeckl, Mathias, Sterz, Fritz, Elrod, JoAnn Broeckel, Nichol, Graham

Journal:

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

5

Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease

Broeckel, Rebecca M., Haese, Nicole, Ando, Takeshi, Dmitriev, Igor, Kreklywich, Craig N., Powers, John, Denton, Michael, Smith, Patricia, Morrison, Thomas E., Heise, Mark, DeFilippis, Victor, Messaoud

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 1.99 MB

english, 2019

6

Pediatric inflammatory bowel disease: Clinical and molecular genetics

Vincent Biank, Ulrich Broeckel, Subra Kugathasan

Journal:

Inflammatory Bowel Diseases

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

7

Pediatric onset Crohn's colitis is characterized by genotype-dependent age-related susceptibility

Arie Levine, Subra Kugathasan, Vito Annese, Vincent Biank, Esther Leshinsky-Silver, Ofir Davidovich, Gad Kimmel, Ron Shamir, Palmieri Orazio, Amir Karban, Ulrich Broeckel, Salvatore Cucchiara

Journal:

Inflammatory Bowel Diseases

Year:

2007

Language:

english

File:

PDF, 146 KB

english, 2007

8

Genome-wide association study identifies single-nucleotide polymorphism inKCNB1associated with left ventricular mass in humans: The HyperGEN Study

Donna K Arnett, Na Li, Weihong Tang, Dabeeru C Rao, Richard B Devereux, Steven A Claas, Rachel Kraemer, Ulrich Broeckel

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 999 KB

english, 2009

9

Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study

Nathan E Wineinger, Amit Patki, Kristin J Meyers, Ulrich Broeckel, Charles C Gu, DC Rao, Richard B Devereux, Donna K Arnett, Hemant K Tiwari

Journal:

BMC Medical Genomics

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

10

Lymphotoxin-α and galectin-2 SNPs are not associated with myocardial infarction in two different German populations

Kamil Sedlacek, Katharina Neureuther, Jakob C. Mueller, Klaus Stark, Marcus Fischer, Andrea Baessler, Wibke Reinhard, Ulrich Broeckel, Wolfgang Lieb, Jeanette Erdmann, Heribert Schunkert, Günter Riegg

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

11

Biologe mit Zephalgien und Fieberschüben

N. Schramm, J. Bogner, N. Broeckel, C. Becker-Gaab

Journal:

Year:

2009

Language:

german

File:

PDF, 437 KB

german, 2009

12

Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men

Frauke Friedrichs, Sonia Brescianini, Vito Annese, Anna Latiano, Klaus Berger, Subra Kugathasan, Ulrich Broeckel, Susanna Nikolaus, Mark J. Daly, Stefan Schreiber, John D. Rioux, Monika Stoll

Journal:

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

13

A locus on chromosome 10 influences C-reactive protein levels in two independent populations

Ulrich Broeckel, Christian Hengstenberg, Bjoern Mayer, Karen Maresso, Daniel Gaudet, Ondrej Seda, Johanne Tremblay, Stephan Holmer, Jeanette Erdmann, Christian Glöckner, Michael Harrison, Lisa J. Mart

Journal:

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

14

BMP4loss-of-function mutations in developmental eye disorders including SHORT syndrome

Linda M. Reis, Rebecca C. Tyler, Kala F. Schilter, Omar Abdul-Rahman, Jeffrey W. Innis, Beth A. Kozel, Adele S. Schneider, Tanya M. Bardakjian, Edward J. Lose, Donna M. Martin, Ulrich Broeckel, Elena

Journal:

Year:

2011

Language:

english

File:

PDF, 1.96 MB

english, 2011

15

Genes for left ventricular hypertrophy

Donna K. Arnett, Lisa de las Fuentes, Ulrich Broeckel

Journal:

Current Hypertension Reports

Year:

2004

Language:

english

File:

PDF, 348 KB

english, 2004

16

Genetic determinants of hypertension: An update

Michael Harrison, Karen Maresso, Ulrich Broeckel

Journal:

Current Hypertension Reports

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

17

A comprehensive linkage analysis for myocardial infarction and its related risk factors

Broeckel, Ulrich, Hengstenberg, Christian, Mayer, Björn, Holmer, Stephan, Martin, Lisa J., Comuzzie, Anthony G., Blangero, John, Nürnberg, Peter, Reis, André, Riegger, Günter A.J.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 581 KB

english, 2002

18

Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and white children with Crohn's disease

Subra Kugathasan, Anthony Loizides, Umesh Babusukumar, Erin McGuire, Tao Wang, Pleasant Hooper, Justin Nebel, Galina Kofman, Richard Noel, Ulrich Broeckel, Vasundhara Tolia

Journal:

Inflammatory Bowel Diseases

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

19

Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping

Ulrich Broeckel, Nicholas J. Schork

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

20

Quality of life after adjuvant chemotherapy for breast cancer

Jo Ann Broeckel, Paul B. Jacobsen, Lodovico Balducci, John Horton, Gary H. Lyman

Journal:

Breast Cancer Research and Treatment

Year:

2000

Language:

english

File:

PDF, 70 KB

english, 2000

21

Sexual Functioning in Long-Term Breast Cancer Survivors Treated with Adjuvant Chemotherapy

Jo A. Broeckel, Christina L. Thors, Paul B. Jacobsen, Margaret Small, Charles E. Cox

Journal:

Breast Cancer Research and Treatment

Year:

2002

Language:

english

File:

PDF, 89 KB

english, 2002

22

PITX2 and FOXC1 spectrum of mutations in ocular syndromes

Reis, Linda M, Tyler, Rebecca C, Volkmann Kloss, Bethany A, Schilter, Kala F, Levin, Alex V, Lowry, R Brian, Zwijnenburg, Petra J G, Stroh, Eliza, Broeckel, Ulrich, Murray, Jeffrey C, Semina, Elena V

Journal:

European Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 700 KB

english, 2012

23

Copy Number Variations Associated With Obesity-Related Traits in African Americans: A Joint Analysis Between GENOA and HyperGEN

Wei Zhao, Nathan E. Wineinger, Hemant K. Tiwari, Thomas H. Mosley, Ulrich Broeckel, Donna K. Arnett, Sharon L.R. Kardia, Edmond K. Kabagambe, Yan V. Sun

Journal:

Year:

2012

Language:

english

File:

PDF, 174 KB

english, 2012

24

Genotype Imputation for African Americans Using Data From HapMap Phase II Versus 1000 Genomes Projects

Yun J. Sung, C. Charles Gu, Hemant K. Tiwari, Donna K. Arnett, Ulrich Broeckel, Dabeeru C. Rao

Journal:

Genetic Epidemiology

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

25

Distinct Heritable Patterns of Angiographic Coronary Artery Disease in Families With Myocardial Infarction

M. Fischer, U. Broeckel, S. Holmer

Journal:

ACC Current Journal Review

Year:

2005

Language:

english

File:

PDF, 41 KB

english, 2005

26

Surgeon Knowledge, Behavior, and Opinions Regarding Intraoperative Cholangiography

Nader N. Massarweh, Allison Devlin, Jo Ann Broeckel Elrod, Rebecca Gaston Symons, David R. Flum

Journal:

Journal of the American College of Surgeons

Year:

2008

Language:

english

File:

PDF, 410 KB

english, 2008

27

Risk Tolerance and Bile Duct Injury: Surgeon Characteristics, Risk-Taking Preference, and Common Bile Duct Injuries

Nader N. Massarweh, Allison Devlin, Rebecca Gaston Symons, Jo Ann Broeckel Elrod, David R. Flum

Journal:

Journal of the American College of Surgeons

Year:

2009

Language:

english

File:

PDF, 728 KB

english, 2009

28

Risk Taking and Tolerance of Uncertainty: Implications for Surgeons

Eric P. Tubbs, Jo Ann Broeckel Elrod, David R. Flum

Journal:

Journal of Surgical Research

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

29

Localization of a Small Genomic Region Associated with Elevated ACE

Xiaofeng Zhu, Colin A. McKenzie, Terrence Forrester, Deborah A. Nickerson, Ulrich Broeckel, Heribert Schunkert, Angela Doering, Howard J. Jacob, Richard S. Cooper, Mark J. Rieder

Journal:

The American Journal of Human Genetics

Year:

2000

Language:

english

File:

PDF, 217 KB

english, 2000

30

Left-ventricular dysfunction

Heribert Schunkert, Ulrich Broeckel, Hans W Hense, Ulrich Keil, Guenter AJ Riegger

Journal:

Year:

1998

Language:

english

File:

PDF, 48 KB

english, 1998

31

Quantitative Founder-Effect Analysis of French Canadian Families Identifies Specific Loci Contributing to Metabolic Phenotypes of Hypertension

P. Hamet, E. Merlo, O. Šeda, U. Broeckel, J. Tremblay, M. Kaldunski, D. Gaudet, G. Bouchard, B. Deslauriers, F. Gagnon, G. Antoniol, Z. Pausová, M. Labuda, M. Jomphe, F. Gossard, G. Tremblay, R. Kirov

Journal:

The American Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 1.41 MB

english, 2005

32

Concordance of DMET Plus Genotyping Results With Those of Orthogonal Genotyping Methods

Fernandez, C A, Smith, C, Yang, W, Lorier, R, Crews, K R, Kornegay, N, Hicks, J K, Stewart, C F, Kawedia, J D, Ramsey, L B, Liu, C, Evans, W E, Relling, M V, Broeckel, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 431 KB

english, 2012

33

Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension

Maloney, J. P., Stearman, R. S., Bull, T. M., Calabrese, D. W., Tripp-Addison, M. L., Wick, M. J., Broeckel, U., Robbins, I. M., Wheeler, L. A., Cogan, J. D., Loyd, J. E.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2012

Language:

english

File:

PDF, 912 KB

english, 2012

34

The associations of body size and body composition with left ventricular mass: impacts for indexation in adults

Hans-Werner Hense, Birgit Gneiting, Michael Muscholl, Ulrich Broeckel, Bernhard Kuch, Angela Doering, Günter A.J Riegger, Heribert Schunkert

Journal:

Journal of the American College of Cardiology

Year:

1998

Language:

english

File:

PDF, 118 KB

english, 1998

35

A Novel Autoinflammatory Disease Due to Homozygous Deletion of the IL-1RN locus; Effective Treatment with Recombinant IL-1 Receptor Antagonist

Verbsky, J., Reddy, S., Suchi, M., Broeckel, U., Hessner, M.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

36

QTL-based association analyses reveal novel genes influencing pleiotropy of metabolic syndrome (MetS)

Zhang, Y., Kent, J.W., Olivier, M., Ali, O., Broeckel, U., Abdou, R.M., Dyer, T.D., Comuzzie, A., Curran, J.E., Carless, M.A., Rainwater, D.L., Göring, H.H.H., Blangero, J., Kissebah, A.H.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.43 MB

english, 2013

37

Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency

R Sebro, H Levy, K Schneck, D Dimmock, BA Raby, CL Cannon, U Broeckel, NJ Risch

Journal:

Clinical Genetics

Year:

2012

Language:

english

File:

PDF, 546 KB

english, 2012

38

Toward the Etiologies of Congenital Heart Diseases

Pelech, Andrew N., Broeckel, Ulrich

Journal:

Clinics in Perinatology

Year:

2005

Language:

english

File:

PDF, 2.37 MB

english, 2005

39

Epidemiology, Risk Factors, and Genetics of High-Altitude–Related Pulmonary Disease

Maloney, James P., Broeckel, Ulrich

Journal:

Clinics in Chest Medicine

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

40

CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn’s disease

KUGATHASAN, S, COLLINS, N, MARESSO, K, HOFFMANN, R, STEPHENS, M, WERLIN, S, RUDOLPH, C, BROECKEL, U

Journal:

Clinical Gastroenterology and Hepatology

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

41

Nod2/card15 mutations and phenotypic correlation in pediatric Crohn's disease (Cd)

Kugathasan, Subra, Collins, Nicole, Maresso, Karen, Matter, Andrea, Sherry, Karen, Rudolph, Colin, Binion, David, Broeckel, Ulrich

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 344 KB

english, 2003

42

The Role of Genomics in the Neonatal ICU

Maresso, Karen, Broeckel, Ulrich

Journal:

Clinics in Perinatology

Year:

2009

Language:

english

File:

PDF, 268 KB

english, 2009

43

Functional Genomics and Its Implications for Molecular Medicine

Broeckel, Ulrich, Maresso, Karen, Kugathasan, Subra

Journal:

Pediatric Clinics of North America

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

44

Obesity–insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice

Kraja, Aldi T., Lawson, Heather A., Arnett, Donna K., Borecki, Ingrid B., Broeckel, Ulrich, de las Fuentes, Lisa, Hunt, Steven C., Province, Michael A., Cheverud, James, Rao, D.C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

45

Development of reusable logic for determination of statin exposure-time from electronic health records

Miller, Aaron W., McCarty, Catherine A., Broeckel, Ulrich, Hytopoulos, Vangelis, Cross, Deanna S.

Journal:

Journal of Biomedical Informatics

Year:

2014

Language:

english

File:

PDF, 949 KB

english, 2014

46

Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children’s Oncology Group

Thompson, Patrick, Wheeler, Heather E., Delaney, Shannon M., Lorier, Rachel, Broeckel, Ulrich, Devidas, Meenakshi, Reaman, Gregory H., Scorsone, Kathleen, Sung, Lillian, Dolan, M. Eileen, Berg, Stacey

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 476 KB

english, 2014

47

Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes

Hicks, J Kevin, Crews, Kristine R, Flynn, Patricia, Haidar, Cyrine E, Daniels, Calvin C, Yang, Wenjian, Panetta, John C, Pei, Deqing, Scott, Jeffrey R, Molinelli, Alejandro R, Broeckel, Ulrich, Bhojwa

Journal:

Pharmacogenomics

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

48

Statistical Methods in Personality Assessment Research

Schinka, John A., LaLone, Leif, Broeckel, Jo Ann

Journal:

Journal of Personality Assessment

Year:

1997

Language:

english

File:

PDF, 669 KB

english, 1997

49

Human gene copy number spectra analysis in congenital heart malformations

Tomita-Mitchell, A., Mahnke, D. K., Struble, C. A., Tuffnell, M. E., Stamm, K. D., Hidestrand, M., Harris, S. E., Goetsch, M. A., Simpson, P. M., Bick, D. P., Broeckel, U., Pelech, A. N., Tweddell, J.

Journal:

Physiological Genomics

Year:

2012

Language:

english

File:

PDF, 6.66 MB

english, 2012

50

Whole-genome copy number variation analysis in anophthalmia and microphthalmia

Schilter, KF, Reis, LM, Schneider, A, Bardakjian, TM, Abdul-Rahman, O, Kozel, BA, Zimmerman, HH, Broeckel, U, Semina, EV

Journal:

Clinical Genetics

Year:

2013

Language:

english

File:

PDF, 794 KB

english, 2013